do, to external surfaces, come under direct observation; they are accompanied with certain other changes in the internal organs, which we shall show to be more destructive still." CHAPTER III. IT CURSES THE BODY.--CONTINUED. We have quoted thus freely in the preceding chapter, in order that the intelligent and thoughtful reader, who is really seeking for the truth in regard to the physical action of alcohol, may be able to gain clear impressions on the subject. The specific changes wrought by this substance on the internal organs are of a most serious character, and should be well understood by all who indulge habitually in its use. EFFECT ON THE MEMBRANES. The parts which first suffer from alcohol are those expansions of the body which the anatomists call the membranes. "The skin is a membranous envelope. Through the whole of the alimentary surface, from the lips downward, and through the bronchial passages to their minutest ramifications, extends the mucous membrane. The lungs, the heart, the liver, the kidneys are folded in delicate membranes, which can be stripped easily from these parts. If you take a portion of bone, you will find it easy to strip off from it a membranous sheath or covering; if you examine a joint, you will find both the head and the socket lined with membranes. The whole of the intestines are enveloped in a fine membrane called _peritoneum_. All the muscles are enveloped in membranes, and the fasciculi, or bundles and fibres of muscles, have their membranous sheathing. The brain and spinal cord are enveloped in three membranes; one nearest to themselves, a pure vascular structure, a net-work of blood-vessels; another, a thin serous structure; a third, a strong fibrous structure. The eyeball is a structure of colloidal humors and membranes, and of nothing else. To complete the description, the minute structures of the vital organs are enrolled in membranous matter." These membranes are the filters of the body. "In their absence there could be no building of structure, no solidification of tissue, nor organic mechanism. Passive themselves, they, nevertheless, separate all structures into their respective positions and adaptations." MEMBRANOUS DETERIORATIONS. In order to make perfectly clear to the reader's mind the action and use